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Efficacy and safety of enzyme PubMed Central (PMC)

May 09, 2014 · To assess the efficacy and safety of enzyme replacement therapy (ERT) with BMN 110 (elosulfase alfa) in patients with Morquio A syndrome (mucopolysaccharidosis IVA).Patients with Morquio A aged 5 years (N = 176) were randomised

A Cardiovascular Disease Linked Gut Microbial Metabolite

Using untargeted metabolomics (n = 1,162 subjects), the plasma metabolite (m/z = 265.1188) phenylacetylglutamine (PAGln) was discovered and then shown in an independent cohort (n = 4,000 subjects) to be associated with cardiovascular disease (CVD) and incident major adverse cardiovascular events (myocardial infarction, stroke, or death).A gut microbiota derived metabolite, PAGln, was

Round Robin Verification of Specimen Temperature During

Round Robin Verification of Specimen Temperature During Accelerated Testing for the PVQAT TG5 Studies David C. MILLER,1* Dennis DIETZ,2 Brian HABERSBERGER,3 Caitlin HALE,2 Fabiana LISCO,4 Wei LUO, Joshua MORSE,1 Nancy PHILLIPS,6 Lorenzo TYLER,2 Sona ULICNA,4 Doug VERMILLION,7 John M. WALLS,4 Peter WILLIAMSON,2 Allen ZIELNIK,2 1National Renewable Energy Laboratory, Golden, CO, USA

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Semiconductor Engineering Deep Insights For Chip

Disclaimer:Semiconductor Engineering/Sperling Media Group LLC ely disclaims the adequacy, accuracy, or completeness of any data and shall not be liable for any errors, omissions or other faults in, delays or interruptions in such data, or for any actions taken in reliance thereon.

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A Cardiovascular Disease Linked Gut Microbial Metabolite

A microbially generated metabolite, PAGIn, is associated with cardiovascular disease and death in humans. Studies in animal models provide insights into PAGIn metabolism as well as its effects in driving platelet invasiveness and thrombosis through adrenergic receptors.

Semiconductor Engineering Deep Insights For Chip

Disclaimer:Semiconductor Engineering/Sperling Media Group LLC ely disclaims the adequacy, accuracy, or completeness of any data and shall not be liable for any errors, omissions or other faults in, delays or interruptions in such data, or for any actions taken in reliance thereon.

A Cardiovascular Disease Linked Gut Microbial Metabolite

Using untargeted metabolomics (n = 1,162 subjects), the plasma metabolite (m/z = 265.1188) phenylacetylglutamine (PAGln) was discovered and then shown in an independent cohort (n = 4,000 subjects) to be associated with cardiovascular disease (CVD) and incident major adverse cardiovascular events (myocardial infarction, stroke, or death).A gut microbiota derived metabolite, PAGln, was

Optimization of Coded Aperture PubMed Central (PMC)

The optimized CA mask derived from this software, and used for all experiments, had the following parametershole diameter Pa = 1.45 mm, number of pixel positions per mask period npm = 62, and mask side 2d = 18.0 cm. Mask thickness (mt) was 1 mm, resulting in 4.2% transmission of 140 keV photons through the opaque portion of the mask.

Liquid metal embedded real time microfluidic flow pressure

The developed PDMS microfluidic pressure sensor is composed of a main flow channel integrated with liquid metal filled sensing channels on both sides (Fig. 1A).All channels in the microfluidic device are 15 m in height, and each sensing channel is separated from the main channel with a 1 m thick membrane, having an aspect ratio of 15.

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Risperidone C23H27FN4O2 PubChem

Risperidone is a benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin effects via cortical 5 HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions.

Telmisartan C33H30N4O2 PubChem

Telmisartan is a member of the class of benzimidazoles used widely in the treatment of hypertension. It has a role as an antihypertensive agent, an angiotensin receptor antagonist, an EC 3.4.15.1 (peptidyl dipeptidase A) inhibitor, a xenobiotic and an environmental contaminant.

Noninvasive Quantification of Cerebral Metabolic Rate for

The insert graph shows the same data focusing around the peak of the AIFs. Although the mean AIF shown here used the whole data set (n = 8), the following analysis on the estimation of AIFs uses a leave one out cross validation method, which excluded the individual data to be estimated from the computation of the standard input function (SIF).

Optimization of Coded Aperture Radioscintigraphy for

May 13, 2011 · Procedures. Equations were derived for the six major dependent variables of CA collimators (i.e., masks) as a function of the ten major independent variables, and an optimized mask was fabricated.After validation, dual modality CA and near infrared (NIR) fluorescence SLN mapping were performed in pigs.

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